Anti-migratory effect of vinflunine in endothelial and glioblastoma cells is associated with changes in EB1 C-terminal detyrosinated/tyrosinated status.

We previously showed that vinflunine, a microtubule-targeting drug of the Vinca-alkaloid family exerted its anti-angiogenic/anti-migratory activities through an increase in microtubule dynamics and an inhibition of microtubule targeting to adhesion sites.Such effect was associated with a reduction of EB1 comet length at microtubule (+) ends.In West

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The effect of microwave stabilization on the properties of whole wheat flour and its further interpretation by molecular docking

Abstract In order to stabilize the whole wheat flour and extend its shelf life, microwave was employed to heat the wheat bran to inactivate the lipase in this paper.The effects of microwave heating of wheat bran on the lipase Music Art activities, gluten properties, dough properties and storage stability of the stabilized whole wheat flour, and the

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High-Performance Nano-Sensing and Slow-Light Applications Based on Tunable Multiple Fano Resonances and EIT-Like Effects in Coupled Plasmonic Resonator System

A basic plasmonic system, consisting of a stub metal-insulator-metal (MIM) waveguide coupled with a ring resonator, is presented to realize Fano resonance and electromagnetically induced transparency-like (EIT-like) effect, which are numerically calculated by the finite element method (FEM).Meanwhile, the formation mechanism of Fano resonance is an

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An International Quiet Ocean Experiment

The effect of noise on marine life is one of the big unknowns of current marine science.Considerable evidence exists that the human contribution to ocean noise has increased during the past few decades: human noise has become the dominant component of marine noise in some regions and noise is directly correlated with the increasing industrializatio

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1-(2-Hydroxyethyl)imidazolidine-2-thione

1-(2-Hydroxyethyl)imidazolidine-2-thione (1) was obtained as a product from an in situ reaction between N-(2-hydroxyethyl)ethylenediamine, carbon disulfide, potassium Essential Oil hydroxide, and di(4-fluorobenzyl)tin dichloride.Compound 1 was characterized by IR, UV, 1H, 13C{1H}, and 2D (COSY, NOESY, HSQC, and HMBC) NMR spectroscopies.The cyclic m

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